We have undertaken numerous field and laboratory trials to test the effect of Citriodiol® on an array of insects.
Leading authorities worldwide now recognise Citriodiol’s first-rate efficacy, making it the only plant-based repellent with this level of global accreditation. There is also a substantial body of data supporting its safety for use on human skin and in particular on young children and babies.
The toxicity profile of Citriodiol® extends to areas beyond acute toxicity assessment. For example, it has no phototoxic potential, is non-mutagenic, passes the chromosome aberration test, is negative for inducing forward mutations at the TK locus in L5178Y mouse lymphoma cells, and is negative in the in-vivo mouse micronucleus assay. In longer-term sub chronic and chronic studies, it is shown to have no adverse reproductive or dermal developmental effect.
In addition to the many toxicological studies done on Citriodiol® to ensure product safety for consumers, Citrefine has also conducted environmental testing to ensure that its products are not harmful to the environment. These tests have proven that Citriodiol® is readily biodegradable, so will not build up to potentially harmful levels in our soils and waterways, unlike many synthetic alternatives such as DEET. Because Citriodiol® is sourced from natural plant oil and is readily biodegradable it is also not toxic to birds, honey bees and other insects beneficial to the environment.
Phys/chem data including stability data is being generated on our product formulations where data gaps exist. A validated method to extract and measure the amount of PMD has been successfully developed for these products and they have proved to be stable in 2-week accelerated stability testing at 54°C.
We are keen to understand and promote the repellence properties of Citriodiol® so if you decide to conduct efficacy testing of your own, we would welcome the opportunity to review your results or even to comment on the proposed study protocol in advance.